There are now about 60 case reports of ALCL in women with breast implants worldwide

In January 2011, articles were published in major US newspapers about the association of lymphoma and breast implants.  This is called anaplastic large cell lymphoma (ALCL), an extremely rare type of malignancy.  Approximately 1 in 500,000 women is diagnosed with ALCL (anywhere in the body) in the United States each year.  Only 3 in 100 million women per year in the US are diagnosed with ALCL in the breast.  Breast ALCL has been most often identified in patients undergoing implant revision operations.  There are now about 60 case reports of ALCL in women with breast implants worldwide.  The total number of implants worldwide is estimated to be between 5-10 million. 

Based on these numbers, for women with breast implants, the estimation is that one out of 125,000 would develop breast ALCL.  To put things in perspective, in the same women, the rate of breast cancer is one out of seven.    According to the FDA (Food and Drug Administration), women with breast implants may have a very small but increased risk of developing this disease in the scar capsule adjacent to the implant.  Fortunately, it does not appear that this lymphoma occurs in the breast tissue itself.  So far, it is not possible to identify a type of implant (silicone versus saline) or a reason for implant (breast cancer reconstruction versus aesthetic augmentation) associated with a smaller or greater risk.  Currently (February 2011), the recommendations are as follows:1)  In women without any abnormal signs or symptoms, breast implants should not be removed due to fear of lymphoma.2)  No screening for lymphoma in breast implant patients who do not have symptoms.

This is because reported cases of breast ALCL had manifestations of chronic fluid pocket (seroma), pain, lumps, swelling, or asymmetry.  Chronic seroma is persistent and recurring, and should be distinguished from post-surgical seromas that commonly happen immediately after breast surgery.  Furthermore, there is no yet identified reliable method to screen for breast ALCL in a non-invasive fashion.3)  If there is suspicion of breast ALCL, the plastic surgeon should collect fresh seroma fluid and representative portions of the capsule (scar around the implant) at the time of surgery and send for pathology tests. 

Diagnostic evaluation should include cytological evaluation of seroma fluid with Wright Giemsa stained smears and cell block immunohistochemistry testing for cluster of differentiation (CD) and Anaplastic Lymphoma Kinase (ALK) markers.4)  If breast ALCL is confirmed, the implant and the capsule around it should be removed.  The patient should be referred to a multi-disciplinary care team with surgical, radiation and medical oncology expertise.  Because this type of Wholesale Wire Passer small Manufacturers malignancy is so rare, there is no defined consensus treatment regimen for the population at large.

Megosztás a facebookon

Silicone gel implants use a silicone gelas their filler

Cohesive gel implants have been used in breast augmentationsurgeries outside the United  States for almost twenty years. There areplenty of customer testimonials and data that support the general belief thatthese new implants might be the greatest implant developed so far. But untilthe FDA approves these implants for unrestricted use in the U.S., American women will have tosettle for either silicone gel or saline breast implants for their breastaugmentation procedures.If you're wondering what the difference is between cohesivegel implants and traditional silicone gel implants, it has to do with the gelitself and the way it is manufactured.

Silicone gel implants use a silicone gelas their filler. This gel is a very thick liquid. Cohesive gel implants are notmade of liquid: their filler is a solid mass of gel that has very similarconsistency and feel to the ever popular Gummy Bear candy.When a cohesive gel implant is created, the manufactureradds what is called a cross-linker to the gel. This cross linker causes the gelto bind together into a solid mass of gel.Both silicone and saline breast implants come in two basicdesign styles: anatomical and round.Round implants are exactly that: round and perfectlysymmetrical. When a woman with round implants lies on her back, her implantswill flatten out like a giant M&M. Although this makes these implantsimpervious to rotation issues, a lot of women don't like the "highprofile" look created by these implants.Anatomical implants are implants that are designed toresemble a real breast. They have more filler near the bottom of the implantthan at the top, and they contain a more natural slope to the implant that isvery similar to how a real breast slopes from its top to its bottom.

Implant rotation is more of a threat to anatomical implantsbecause if they rotate, they will obviously appear out of place (and usually ina very unsightly fashion). Any woman who has experienced a rotated anatomicalimplant will attest to the fact that it is very upsetting to say the least.Cohesive gel implants, due to the way they are designed as asolid mass of gel, are only available in anatomical design. Because they areonly available as an anatomically shaped implant, they are also only availablewith a textured surface and not a smooth surface. A textured implant will beless likely to rotate, and in the case of anatomically shaped implants, this isa very important feature to help thwart implant rotation.If you are interested in the latest implant to hit the U.S. market,the cohesive gel implant, you will need to speak with a surgeon who has beenapproved by the FDA for the cohesive gel clinical trial.

Once you find asurgeon, give him or her a call and schedule an initial consultation.If you prefer traditional silicone gel or saline implants,then you can contact any licensed Wire Tighter with Cutter Suppliers, board certified plastic surgeon whospecializes in breast augmentation. Ask for a free initial consultation, andthen meet with the surgeon and ask your questions.Please do not interpret the content of this article asmedical advice. Only a licensed, practicing physician should answer yourquestions regarding health or plastic surgery related topics. 

Megosztás a facebookon